Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/79815| Title: | Stable triterpenoid iminium salts and their activity as inhibitors of butyrylcholinesterase |
| Author(s): | Heise, Niels V. Ströhl, Dieter Schmidt, Theresa Csuk, René |
| Issue Date: | 2022 |
| Type: | Article |
| Language: | English |
| Abstract: | Amides derived from platanic acid (30-nor-lupane skeleton) were converted in two steps into 21-aza-17,19-ethano-19-nor-urs-20-en-21-ium chlorides. These ursane-skeleton iminium salts are first in their class, and some of them proved as selective inhibitors of the enzyme butyrylcholinesterase while holding no inhibitory activity for acetylcholinesterase. |
| URI: | https://opendata.uni-halle.de//handle/1981185920/81769 http://dx.doi.org/10.25673/79815 |
| Open Access: |  Open access publication |
| License: |  (CC BY 4.0) Creative Commons Attribution 4.0 |
| Sponsor/Funder: | Publikationsfonds MLU |
| Journal Title: | Journal of molecular structure |
| Publisher: | Elsevier |
| Publisher Place: | New York, NY [u.a.] |
| Volume: | 1249 |
| Original Publication: | 10.1016/j.molstruc.2021.131646 |
| Appears in Collections: | Open Access Publikationen der MLU |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 1-s2.0-S0022286021017749-main.pdf | 941.56 kB | Adobe PDF |  View/Open |