Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/35178
Title: Different strategies to prepare anti-inflammatory biomaterial coatings with in vitro and in vivo studies on efficacy and mechanisms : [kumulative Dissertation]
Author(s): Alkhoury, HalaLook up in the Integrated Authority File of the German National Library
Referee(s): Groth, ThomasLook up in the Integrated Authority File of the German National Library
Pietzsch, MarkusLook up in the Integrated Authority File of the German National Library
Gallego Ferrer, Gloria
Granting Institution: Martin-Luther-Universität Halle-Wittenberg
Issue Date: 2020
Extent: 1 Online-Ressource (146 Seiten)
Type: HochschulschriftLook up in the Integrated Authority File of the German National Library
Type: Doctoral thesis
Exam Date: 2020-11-23
Language: English
URN: urn:nbn:de:gbv:3:4-1981185920-353883
Abstract: Chronische Entzündungen und fibröse Verkapselungen, die nach der Implantation von Biomaterialien auftreten können, schränken die Funktion von Implantaten stark ein. Diese Arbeit zielte daher darauf ab, neuartige Beschichtungen für verschiedene biomedizinische Anwendungen zu entwickeln, bei denen Glykosaminoglykane wie Hyaluronan und Heparin eingesetzt werden, da vor allem Heparin und hochmolekulare Hyaluronsäure für eine entzündungshemmende Wirkung bekannt sind.
Chronic inflammation and fibrous encapsulation, which can occur after the implantation of biomaterials, severely limit the function of implants. This work was aimed to develop novel implant coatings for various biomedical applications using glycosaminoglycans such as hyaluronan, and heparin, since heparin and high-molecular hyaluronic acid are known to have anti-inflammatory effects.
URI: https://opendata.uni-halle.de//handle/1981185920/35388
http://dx.doi.org/10.25673/35178
Open Access: Open access publication
License: In Copyright
Appears in Collections:Interne-Einreichungen

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