Safety first : das Ubiquitin-Proteasom-System (UPS) und die Photosynthese

Abstract

The proteasome is essential for the control of protein turnover in the nucleus and the cytosol of eukaryotic cells. Chloroplasts and mitochondria import thousands of nuclear-encoded proteins as precursor proteins from the cytosol. We show that mild genetic proteasome impairment interferes with a cytosolic equilibrium between precursor protein import and degradation resulting in elevated precursor protein abundance in the cytosol and improved photosynthetic performance.