Isolation and Identification of Bacteria Isolated from the Oral Cavity of Oral Leukoplakia

Abstract

A potentially cancerous condition called oral leucoplakia (OL) is typified by white patches on the oral mucosa. Microbial colonization, especially by bacteria, has a role in the pathophysiology of OL by promoting inflammation and the advancement of the illness. In this study, bacterial species from the oral cavity of patients with OL will be isolated, identified, and compared to those found in healthy persons. From July to December 2024, samples were taken from dental clinics and specialty centers in the Diyala Governorate. Micrococcus luteus, Kocuria kristinae pneumonia, Streptococcus alactolyticus, Staphylococcus hominis, and Rothia dentocariosa were among the most commonly isolated bacterial species. The development and malignant transformation of oral leukoplakia may be facilitated by the presence of particular pathogenic microorganisms. Thirty of the 120 MDR bacterial samples showed antibacterial sensitivity, indicating a possible role in chronic inflammation and the development of disease. To better understand how these bacteria contribute to the pathophysiology of OL and create focused treatment plans, more investigation is needed.