Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/13892
Title: Enzymatic synthesis and characterization of grafted polyesters and their use as steric stabilizers for cubosomes
Author(s): Bilal, Muhammad Humayun
Referee(s): Kreßler, Jörg
Bruns, Niko
Granting Institution: Martin-Luther-Universität Halle-Wittenberg
Issue Date: 2019
Extent: 1 Online-Ressource (115 Seiten)
Type: HochschulschriftLook up in the Integrated Authority File of the German National Library
Type: PhDThesis
Exam Date: 2019-03-11
Language: English
URN: urn:nbn:de:gbv:3:4-24545
Subjects: PolyesterLook up in the Integrated Authority File of the German National Library
Chemische SyntheseLook up in the Integrated Authority File of the German National Library
StabilisatorLook up in the Integrated Authority File of the German National Library
NanopartikelLook up in the Integrated Authority File of the German National Library
Abstract: In der vorliegenden Arbeit wurden biologisch abbaubare Polyester durch enzymatische Synthese hergestellt und durch Pfropfung mit gesättigten und ungesättigten Fettsäuren modifiziert. Die synthetisierten Polymere wurden umfassend charakterisiert und ihre Selbstorganisation in wässrigen Lösungen untersucht. Des Weiteren wurden die mit ungesättigten Fettsäuren modifizierten Polyester durch weitere Pfropfung mit Polyethylenglycol (PEG) wasserlöslich gemacht und hinsichtlich ihrer sterischen stabilisierenden Eigenschaften für kubisch flüssigkristalline Nanopartikel (Cubosomen) in Mischungen mit Glycerolmonooleat untersucht.
In this work, enzymatic synthesis of biodegradable polyesters followed by their grafting with saturated and unsaturated fatty acid has been undertaken. Polymer synthesis has been thoroughly investigated through comprehensive characterization as well as their self-assembled behaviour in aqueous media. Furthermore, unsaturated fatty acid grafted polyesters were additionally grafted by poly(ethylene glycol) (PEG) in order to make them water soluble. These muligraft polymers were afterwards studied as steric stabilizers for cubic liquid crystalline nanoparticles (cubosomes) of glycerol monooleate.
URI: https://opendata.uni-halle.de//handle/1981185920/14019
http://dx.doi.org/10.25673/13892
Open Access: Open access publication
License: In CopyrightIn Copyright
Appears in Collections:Chemie und zugeordnete Wissenschaften

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