Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/35667
Title: Calcium vs. Pentagastrin Stimulation bei der C-Zell-Erkrankung der Schilddrüse : eine Matched-Pair Analyse
Author(s): Elwerr, MalikLook up in the Integrated Authority File of the German National Library
Referee(s): Lorenz, KerstinLook up in the Integrated Authority File of the German National Library
Rayes, NadaLook up in the Integrated Authority File of the German National Library
Holzer, Katharina
Granting Institution: Martin-Luther-Universität Halle-Wittenberg
Issue Date: 2020
Extent: 1 Online-Ressource (64 Seiten)
Type: HochschulschriftLook up in the Integrated Authority File of the German National Library
Type: PhDThesis
Exam Date: 2020-11-20
Language: German
URN: urn:nbn:de:gbv:3:4-1981185920-358857
Abstract: Calcitonin stimulation testing aims at defining the underlying type of c-cell disease (CCD) in order to customize appropriate timing and extent of surgery or consider observation. The importance of stimulation testing is widely accepted in hereditary CCD and the follow-up of MTC, while its role in sporadic forms is controversial. Importantly, calcium (Ca2+) stimulation testing lacks comparison to established recommendations based on reliable cut-off values using Pentagastrin (Pg). This study investigates the correlation of Ca2+- and Pg-stimulation testing in CCD. In a matched pair analysis, Pg- and Ca2+ -stimulation testing for calcitonin (Ct) was compared in 295 patients with c-cell hyperplasia (CCH) and with medullary thyroid cancer confined to the thyroid (Tx N0 M0) undergoing primary surgery.
Calcitonin stimulation testing aims at defining the underlying type of c-cell disease (CCD) in order to customize appropriate timing and extent of surgery or consider observation. The importance of stimulation testing is widely accepted in hereditary CCD and the follow-up of MTC, while its role in sporadic forms is controversial. Importantly, calcium (Ca2+) stimulation testing lacks comparison to established recommendations based on reliable cut-off values using Pentagastrin (Pg). This study investigates the correlation of Ca2+- and Pg-stimulation testing in CCD. In a matched pair analysis, Pg- and Ca2+ -stimulation testing for calcitonin (Ct) was compared in 295 patients with c-cell hyperplasia (CCH) and with medullary thyroid cancer confined to the thyroid (Tx N0 M0) undergoing primary surgery.
URI: https://opendata.uni-halle.de//handle/1981185920/35885
http://dx.doi.org/10.25673/35667
Open Access: Open access publication
License: In CopyrightIn Copyright
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