Please use this identifier to cite or link to this item:
Title: Increased blood flow velocity in middle cerebral artery and headache upon ingestion of ice water
Author(s): Hensel, Ole
Burow, Philipp
Mages, Stephan
Wienke, AndreasLook up in the Integrated Authority File of the German National Library
Kraya, TorstenLook up in the Integrated Authority File of the German National Library
Zierz, StephanLook up in the Integrated Authority File of the German National Library
Issue Date: 2019
Type: Article
Language: English
Abstract: Introduction: “Headache attributed to ingestion or inhalation of a cold stimulus” (HICS) is one of the most common primary headache disorders. Little is known about the pathophysiology of HICS and other headache disorders. The aim of this study was to analyze mean flow velocity (MFV) and cerebrovascular resistance (RI) in both middle cerebral arteries (MCA) upon ingestion of ice water. Methods: The MFV and RI in both MCAs was continuously measured by transcranial sonography. HICS was induced by drinking 200 ml of ice water. Results: In all volunteers, the ingestion of ice water led to a decrease in RI, which was accompanied by an increase in MFV. In volunteers with induced HICS, MFV were significantly higher compared to volunteers that did not experience HICS. In volunteers with HICS, MFV increased even more significantly when lacrimation occurred compared to volunteers in which it did not. In volunteers without induced HICS, MFV was higher in those volunteers with a positive history of HICS than in those with a negative HICS history. Conclusion: This study revealed a raised MFV upon ingestion of ice water. Volunteers with a provoked case of HICS had a higher MFV than volunteers without HICS. The increase in MFV was even higher when the headache was accompanied by lacrimation. This may indicate an involvement of the trigeminal-parasympathetic vasodilator reflex.
Open Access: Open access publication
License: (CC BY 4.0) Creative Commons Attribution 4.0(CC BY 4.0) Creative Commons Attribution 4.0
Sponsor/Funder: Publikationsfond MLU
Journal Title: Frontiers in neurology
Publisher: Frontiers Research Foundation
Publisher Place: Lausanne
Volume: 10
Issue: 677
Original Publication: 10.3389/fneur.2019.00677
Appears in Collections:Open Access Publikationen der MLU

Files in This Item:
File Description SizeFormat 
fneur-10-00677.pdf589.39 kBAdobe PDFThumbnail