Please use this identifier to cite or link to this item:
Title: Zinc deficiency : an independent risk factor in the pathogenesis of haemorrhagic stroke?
Author(s): Grüngreiff, KurtLook up in the Integrated Authority File of the German National Library
Gottstein, Thomas
Reinhold, Dirk
Issue Date: 2020
Type: Article
Language: English
URN: urn:nbn:de:gbv:ma9:1-1981185920-366224
Subjects: Zinc functions
Food composition
Zinc deficiency
Zinc resorption
Abstract: Zinc is an essential trace element for human health and plays a fundamental role in metabolic, immunological and many other biological processes. The e ects of zinc are based on the intra- and extracellular regulatory function of the zinc ion (Zn2+) and its interactions with proteins. The regulation of cellular zinc homeostasis takes place via a complex network of metal transporters and bu ering systems that react to changes in the availability of zinc in nutrition, chronic diseases, infections and many other processes. Zinc deficiency is associated with impairment of numerous metabolic processes, reduced resistance to infections due to impaired immune functions, changes in skin and its appendages and disorders of wound healing and haemostasis. While ischemic heart attacks (myocardial infarction) occur more frequently with meat-based normal diets, haemorrhagic strokes are more frequently observed with vegetarian/vegan diets. The causes are discussed as deficiencies of various micronutrients, such as vitamin B12, vitamin D, various amino acids and also zinc. In the present review, after a description of the functions of zinc and its resorption, a discussion of daily food intake will follow, with a special focus on the importance of food composition and preparation for the zinc balance. The close interrelationships between proteins, especially albumin and zinc will be discussed. Finally, the possible causes and consequences of a zinc deficiency on the blood vessels and blood coagulation are considered.
Open Access: Open access publication
License: (CC BY 4.0) Creative Commons Attribution 4.0(CC BY 4.0) Creative Commons Attribution 4.0
Sponsor/Funder: DFG-Publikationsfonds 2020
Journal Title: Nutrients
Publisher: MDPI
Publisher Place: Basel
Volume: 12
Issue: 11
Original Publication: 10.3390/nu12113548
Page Start: 1
Page End: 11
Appears in Collections:Medizinische Fakultät (OA)

Files in This Item:
File Description SizeFormat 
Gruengreiff et al._Zinc deficiency_2020.pdfZweitveröffentlichung398.07 kBAdobe PDFThumbnail