Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/97331
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dc.contributor.authorSchöninger, Lucas-
dc.contributor.authorVoigt-Zimmermann, Susanne-
dc.contributor.authorKropf, Siegfried-
dc.contributor.authorArens, Christoph-
dc.contributor.authorDavaris, Nikolaos-
dc.date.accessioned2023-01-16T10:33:21Z-
dc.date.available2023-01-16T10:33:21Z-
dc.date.issued2021-
dc.date.submitted2021-
dc.identifier.urihttps://opendata.uni-halle.de//handle/1981185920/99287-
dc.identifier.urihttp://dx.doi.org/10.25673/97331-
dc.description.abstractBackground Perpendicular vascular changes (PVC) are markers of tumor-induced neoangiogenesis at the vocal folds. Contact endoscopy with narrow-band imaging (CE-NBI) allows a detailed analysis of such vascular changes. Objective This work intends to evaluate the potential of CE-NBI for diagnosis of benign, dysplastic, and malignant lesions of the vocal folds. In addition, it should be determined whether CE-NBI offers an additional benefit in detecting PVC compared to white-light endoscopy (WLE) and NBI alone. Materials and methods Three examiners evaluated histologically verified cases of benign, dysplastic, and malignant lesions of the larynx in WLE, NBI, and CE-NBI (n = 60). In each mode, they examined the lesion for PVC and assessed the lesion’s dignity. The proportion of lesions with detected PVC, the statistical measures of performance in detecting high-grade dysplasia and carcinoma, and the interrater variability for each mode were calculated. Results CE-NBI proved superior to the other investigated diagnostic methods in terms of detecting PVC and in terms of sensitivity and accuracy in the diagnosis of high-grade dysplasia and carcinoma. A clear association of such pathologies with PVC was seen. Conclusion CE-NBI detects PVC more frequently and reliably than the other methods investigated. The association of these vascular patterns to high-grade dysplasia and vocal fold carcinomas could be confirmed. Compared to WLE and NBI endoscopy, the diagnostic quality for detecting high-grade dysplasia and carcinoma is increased. Thus, CE-NBI can improve endoscopic differentiation between benign and malignant lesions of the vocal folds by enhancing the detection of PVC.eng
dc.description.sponsorshipProjekt DEAL 2021-
dc.language.isoger-
dc.relation.ispartofhttp://link.springer.com/journal/106-
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subjectLaryngoscopyeng
dc.subjectDiagnostic imagingeng
dc.subjectLaryngeal neoplasmseng
dc.subjectPathologic neovascularizationeng
dc.subjectLaryngeal diseaseseng
dc.subject.ddc610.72-
dc.titleKontaktendoskopie mit Narrow Band Imaging zur Erkennung perpendikulärer Gefäßveränderungen bei benignen Läsionen, Dysplasien und Karzinomen der Stimmlippenger
dc.typeArticle-
dc.title.translatedContact endoscopy with narrow-band imaging for detection of perpendicular vascular changes in benign, dysplastic, and malignant lesions of the vocal folds-
dc.identifier.urnurn:nbn:de:gbv:ma9:1-1981185920-992873-
local.versionTypepublishedVersion-
local.bibliographicCitation.journaltitleHNO-
local.bibliographicCitation.volume69-
local.bibliographicCitation.issue9-
local.bibliographicCitation.pagestart712-
local.bibliographicCitation.pageend718-
local.bibliographicCitation.publishernameSpringer-
local.bibliographicCitation.publisherplaceBerlin-
local.bibliographicCitation.doi10.1007/s00106-021-01063-8-
local.subject.keywordsLaryngoscopy, Diagnostic imaging, Laryngeal neoplasms, Pathologic neovascularization, Laryngeal diseases-
local.openaccesstrue-
dc.identifier.ppn1762472546-
local.bibliographicCitation.year2021-
cbs.sru.importDate2023-01-16T10:29:14Z-
local.bibliographicCitationEnthalten in HNO - Berlin : Springer, 1996-
local.accessrights.dnbfree-
Appears in Collections:Medizinische Fakultät (OA)

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