Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/101929
Title: | Sensitivity Analysis of Enzyme-Substrate-Inhibitor Interaction Based on Nonlinear Dynamic Model |
Author(s): | Martensyuk, Vasyl Klos-Witkowska, Aleksandra |
Granting Institution: | Hochschule Anhalt |
Issue Date: | 2023 |
Extent: | 1 Online-Ressource (10 Seiten) |
Language: | English |
Abstract: | The development of electrochemical biosensors is cutting-edge in current research in medicine, biology, and ecology. The modeling and study of the enzyme-substrate-inhibitor interaction are required for biosensor design. The aim of the paper is to construct a three-stage model for an electrochemical biosensor and to perform its sensitivity analysis. The research is based on the Morris method. The main results are concerning the comparative impact of the model parameters related to biochemical reaction rates on the dynamics of the changes of the concentrations of enzyme, substrate, inhibitor, three complexes, and the reaction product throughout three stages. The results have both theoretical and practical relevance as the model parameters studied come from a real case study of biosensors for alpha-chaconine. |
URI: | https://opendata.uni-halle.de//handle/1981185920/103880 http://dx.doi.org/10.25673/101929 |
Open Access: | ![]() |
License: | ![]() |
Appears in Collections: | International Conference on Applied Innovations in IT (ICAIIT) |
Files in This Item:
File | Description | Size | Format | |
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3_1 ICAIIT_2023_paper_780.pdf | 1.48 MB | Adobe PDF | ![]() View/Open |