Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/36477
Title: | Aseptic bone-flap resorption after cranioplasty : incidence and risk factors |
Author(s): | Rashidi, Ali![]() Sandalcioglu, I. Erol ![]() Luchtmann, Michael ![]() |
Issue Date: | 2020 |
Type: | Article |
Language: | English |
URN: | urn:nbn:de:gbv:ma9:1-1981185920-367094 |
Subjects: | Bone-flap resorption Cranioplasty Risk factors |
Abstract: | Objective One of the common complications occurring after cranioplasty (CP) is aseptic bone-flap resorption (ABFR). Reoperation necessary because of the development of ABFR can lead to unfavorable complications during subsequent surgery using a synthetic skull implant, and also necessarily leads to higher costs. The aim of this study is to identify prognostic factors that may help to predict the development of ABFR. Methods In this study, 303 CP surgeries performed between 2002 and 2017 were examined retrospectively to identify factors predicting the occurrence of ABFR. A number of these factors (e.g., time lapse between decompressive craniectomy (DC) and CP, bone-flap size, specific laboratory signs, and the reason for the original DC) were analyzed as possibly influencing the risk of developing ABFR. Results ABFR of an autologous bone flap that subsequently required a CP with synthetic skull implants occurred in 10 of 303 patients (3.0%). CP timing and patients’ Karnofsky Performance Scores (KPS) (p = 0.008; p = 0.012) were identified as significant factors with an impact on the development of ABRF. Age did not reveal a significant value, but statistical analysis shows a clear trend. The younger the age, the more likely it was that an ABFR would develop. Conclusion The risk of ABFR lessens the longer the period of time elapsed between DC and CP. Age does not reveal a significant value, but statistical analysis shows that there is a clear trend. |
URI: | https://opendata.uni-halle.de//handle/1981185920/36709 http://dx.doi.org/10.25673/36477 |
Open Access: | ![]() |
License: | ![]() |
Sponsor/Funder: | DFG-Publikationsfonds 2020 |
Journal Title: | PLOS ONE |
Publisher: | PLOS |
Publisher Place: | San Francisco, California, US |
Volume: | 15 |
Issue: | 1 |
Original Publication: | 10.1371/journal.pone.0228009 |
Page Start: | 1 |
Page End: | 10 |
Appears in Collections: | Medizinische Fakultät (OA) |
Files in This Item:
File | Description | Size | Format | |
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Rashidi et al._Aseptic_2020.pdf | Zweitveröffentlichung | 491.15 kB | Adobe PDF | ![]() View/Open |