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http://dx.doi.org/10.25673/103441
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DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Hoenke, Sophie | - |
dc.contributor.author | Brandes, Benjamin | - |
dc.contributor.author | Csuk, René | - |
dc.date.accessioned | 2023-06-06T07:03:52Z | - |
dc.date.available | 2023-06-06T07:03:52Z | - |
dc.date.issued | 2023 | - |
dc.identifier.uri | https://opendata.uni-halle.de//handle/1981185920/105395 | - |
dc.identifier.uri | http://dx.doi.org/10.25673/103441 | - |
dc.description.abstract | In search of suitable tool to target the endoplasmic reticulum of human tumor cells, a non-cytotoxic aza-BODIPY derivative was designed and accessed in a simple synthesis in a few steps from commercially available starting materials. This aza-BODIPY was conjugated to 3-O-acetyl-triterpene carboxylic acids (glycyrrhetinic, ursolic, oleanolic, and betulinic acid) using a piperazinyl spacer. The resulting conjugates exhibited no cytotoxicity but were able to selectively target the ER. | eng |
dc.language.iso | eng | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject.ddc | 540 | - |
dc.title | Non-cytotoxic aza-BODIPY triterpene conjugates to target the endoplasmic reticulum | eng |
dc.type | Article | - |
local.versionType | publishedVersion | - |
local.bibliographicCitation.journaltitle | European journal of medicinal chemistry reports | - |
local.bibliographicCitation.volume | 7 | - |
local.bibliographicCitation.publishername | Elsevier | - |
local.bibliographicCitation.publisherplace | Amsterdam | - |
local.bibliographicCitation.doi | 10.1016/j.ejmcr.2022.100099 | - |
local.subject.keywords | Triterpenes, aza BODIPY, Endoplasmic reticulum, Malignant cells | - |
local.openaccess | true | - |
dc.identifier.ppn | 1847459625 | - |
local.bibliographicCitation.year | 2023 | - |
cbs.sru.importDate | 2023-06-06T07:03:22Z | - |
local.bibliographicCitation | Enthalten in European journal of medicinal chemistry reports - Amsterdam : Elsevier, 2021 | - |
local.accessrights.dnb | free | - |
Enthalten in den Sammlungen: | Open Access Publikationen der MLU |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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1-s2.0-S2772417422000711-main.pdf | 1.08 MB | Adobe PDF | ![]() Öffnen/Anzeigen |