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Title: Long-term psychosocial consequences of whole-body magnetic resonance imaging and reporting of incidental findings in a population-based cohort study
Author(s): Korbmacher-Böttcher, DorinaLook up in the Integrated Authority File of the German National Library
Bamberg, Fabian
Peters, Annette
Linkohr, Birgit
Ladwig, Karl-Heinz
Schwettmann, LarsLook up in the Integrated Authority File of the German National Library
Weckbach, SabineLook up in the Integrated Authority File of the German National Library
Schlett, Christopher L.
Rospleszcz, Susanne
Issue Date: 2022
Type: Article
Language: English
Abstract: Management of radiological incidental findings (IF) is of rising importance; however, psychosocial implications of IF reporting remain unclear. We compared long-term psychosocial effects between individuals who underwent whole-body magnetic resonance imaging (MRI) with and without reported IF, and individuals who did not undergo imaging. We used a longitudinal population-based cohort from Western Europe. Longitudinal analysis included three examinations (exam 1, 6 years prior to MRI; exam 2, MRI; exam 3, 4 years after MRI). Psychosocial outcomes included PHQ-9 (Patient Health Questionnaire), DEEX (Depression and Exhaustion Scale), PSS-10 (Perceived Stress Scale) and a Somatization Scale. Univariate analyses and adjusted linear mixed models were calculated. Among 855 included individuals, 25% (n = 212) underwent MRI and 6% (n = 50) had at least one reported IF. Compared to MRI participants, non-participants had a higher psychosocial burden indicated by PHQ-9 in exam 1 (3.3 ± 3.3 vs. 2.5 ± 2.3) and DEEX (8.6 ± 4.7 vs. 7.7 ± 4.4), Somatization Scale (5.9 ± 4.3 vs. 4.8 ± 3.8) and PSS-10 (14.7 ± 5.7 vs. 13.7 ± 5.3, all p < 0.05) in exam 3. MRI participation without IF reporting was significantly associated with lower values of DEEX, PHQ-9 and Somatization Scale. There were no significant differences at the three timepoints between MRI participants with and without IF. In conclusion, individuals who voluntarily participated in whole-body MRI had less psychosocial burden and imaging and IF reporting were not associated with adverse long-term psychosocial consequences. However, due to the study design we cannot conclude that the MRI exam itself represented a beneficial intervention causing improvement in mental health scores.
Open Access: Open access publication
License: (CC BY 4.0) Creative Commons Attribution 4.0(CC BY 4.0) Creative Commons Attribution 4.0
Journal Title: Diagnostics
Publisher: MDPI
Publisher Place: Basel
Volume: 12
Issue: 10
Original Publication: 10.3390/diagnostics12102356
Page Start: 1
Page End: 16
Appears in Collections:Open Access Publikationen der MLU

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