Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/110897Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hipper, Elena | - |
| dc.contributor.author | Blech, Michaela | - |
| dc.contributor.author | Hinderberger, Dariush | - |
| dc.contributor.author | Garidel, Patrick | - |
| dc.contributor.author | Kaiser, Wolfgang | - |
| dc.date.accessioned | 2023-10-10T11:09:19Z | - |
| dc.date.available | 2023-10-10T11:09:19Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.uri | https://opendata.uni-halle.de//handle/1981185920/112852 | - |
| dc.identifier.uri | http://dx.doi.org/10.25673/110897 | - |
| dc.description.abstract | UV and ambient light-induced modifications and related degradation of therapeutic proteins are observed during manufacturing and storage. Therefore, to ensure product quality, protein formulations need to be analyzed with respect to photo-degradation processes and eventually protected from light exposure. This task usually demands the application and combination of various analytical methods. This review addresses analytical aspects of investigating photo-oxidation products and related mediators such as reactive oxygen species generated via UV and ambient light with well-established and novel techniques. | eng |
| dc.language.iso | eng | - |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
| dc.subject.ddc | 540 | - |
| dc.title | Photo-oxidation of therapeutic protein formulations : from radical formation to analytical techniques | eng |
| dc.type | Article | - |
| local.versionType | publishedVersion | - |
| local.bibliographicCitation.journaltitle | Pharmaceutics | - |
| local.bibliographicCitation.volume | 14 | - |
| local.bibliographicCitation.issue | 1 | - |
| local.bibliographicCitation.pagestart | 1 | - |
| local.bibliographicCitation.pageend | 50 | - |
| local.bibliographicCitation.publishername | MDPI | - |
| local.bibliographicCitation.publisherplace | Basel | - |
| local.bibliographicCitation.doi | 10.3390/pharmaceutics14010072 | - |
| local.subject.keywords | photo-degradation; analytical methods; post-translational modification; protein degradation; reactive oxygen species | - |
| local.openaccess | true | - |
| dc.identifier.ppn | 1861157193 | - |
| cbs.publication.displayform | 2022 | - |
| local.bibliographicCitation.year | 2022 | - |
| cbs.sru.importDate | 2023-10-10T11:08:52Z | - |
| local.bibliographicCitation | Enthalten in Pharmaceutics - Basel : MDPI, 2009 | - |
| local.accessrights.dnb | free | - |
| Appears in Collections: | Open Access Publikationen der MLU | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| pharmaceutics-14-00072-v3.pdf | 4.24 MB | Adobe PDF |  View/Open |