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Title: Equipercentile equating of scores from common patient-reported outcome measures of physical function in patients with cancer
Author(s): Rothmund, Maria
Pilz, Micha J.
Schlosser, Lisa
Arraras, Juan I.
Groenvolde, Mogens
Holzner, Bernhard
Leeuwen, MariekeLook up in the Integrated Authority File of the German National Library
Petersen, Morten Aa.
Schmidt, Heike
Young, Teresa
Rose, MatthiasLook up in the Integrated Authority File of the German National Library
Cella, David
Giesinger, Johannes M.
Issue Date: 2024
Type: Article
Language: English
Abstract: Objective: To provide equipercentile equating of physical function (PF) scores from frequently used patient-reported outcome measures (PROMs) in cancer patients to facilitate data pooling and comparisons. Study Design and Setting: Adult cancer patients from five European countries completed the European Organization for Research and Treatment of Cancer (EORTC) computer adaptive test (CAT) Core, EORTC Quality of Life Questionnaire Version 3.0 (QLQ-C30), Functional Assessment of Cancer Therapy - General (FACT-G), 36-item Short Form Health Survey (SF-36), and the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function 20a short form. The R package “equate” was used to establish conversion tables of PF scores on those measures with a bivariate rank correlation of at least 0.75. Results: In total, 953 patients with cancer (mean age 58.9 years, 54.7% men) participated. Bivariate rank correlations between PF scores from the EORTC CAT Core, EORTC QLQ-C30, SF-36, and PROMIS were all above 0.85, but below 0.69 for the FACT-G. Conversion tables were established for all measures but the FACT-G. These tables indicate which score from one PROM best matches the score from another PROM and provide standard errors of converted scores. Conclusion: Our analysis indicates that linking of PF scores from both EORTC measures (CAT and QLQ-C30) with PROMIS and SF-36 is possible, whereas the physical domain of the FACT-G seems to be different. The established conversion tables may be used for comparing results or pooling data from clinical studies using different PROMs.
Open Access: Open access publication
License: (CC BY 4.0) Creative Commons Attribution 4.0(CC BY 4.0) Creative Commons Attribution 4.0
Journal Title: Journal of clinical epidemiology
Publisher: Elsevier Science
Publisher Place: Amsterdam [u.a.]
Volume: 165
Original Publication: 10.1016/j.jclinepi.2023.10.019
Page Start: 1
Page End: 12
Appears in Collections:Open Access Publikationen der MLU

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