Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/116541
Title: | Comparative metabolite analysis of Piper sarmentosum organs approached by LC–MS-based metabolic profiling |
Author(s): | Ware, Ismail Bin![]() Franke, Katrin ![]() Frolov, Andrej ![]() Bureiko, Kseniia Kysil, Elana Yahayu, Maizatulakmal El-Enshasy, Hesham A. ![]() Wessjohann, Ludger ![]() |
Issue Date: | 2024 |
Type: | Article |
Language: | English |
Abstract: | Piper sarmentosum Roxb. (Piperaceae) is a traditional medicinal and food plant widely distributed in the tropical and subtropical regions of Asia, offering both health and culinary benefits. In this study the secondary metabolites in different organs of P. sarmentosum were identified and their relative abundances were characterized. The metabolic profiles of leaves, roots, stems and fruits were comprehensively investigated by liquid chromatography high-resolution mass spectrometry (LC-HR-MS) and the data subsequently analyzed using multivariate statistical methods. Manual interpretation of the tandem mass spectrometric (MS/MS) fragmentation patterns revealed the presence of 154 tentatively identified metabolites, mostly represented by alkaloids and flavonoids. Principle component analysis and hierarchical clustering indicated the predominant occurrence of flavonoids, lignans and phenyl propanoids in leaves, aporphines in stems, piperamides in fruits and lignan-amides in roots. Overall, this study provides extensive data on the metabolite composition of P. sarmentosum, supplying useful information for bioactive compounds discovery and patterns of their preferential biosynthesis or storage in specific organs. This can be used to optimize production and harvesting as well as to maximize the plant’s economic value as herbal medicine or in food applications. |
URI: | https://opendata.uni-halle.de//handle/1981185920/118498 http://dx.doi.org/10.25673/116541 |
Open Access: | ![]() |
License: | ![]() |
Journal Title: | Natural products and bioprospecting |
Publisher: | Springer |
Publisher Place: | Heidelberg |
Volume: | 30 |
Original Publication: | 10.1007/s13659-024-00453-z |
Page Start: | 1 |
Page End: | 21 |
Appears in Collections: | Open Access Publikationen der MLU |
Files in This Item:
File | Description | Size | Format | |
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s13659-024-00453-z.pdf | 2.87 MB | Adobe PDF | ![]() View/Open |