Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/120754| Title: | Endogenous retroviruses in nervous system disorders |
| Author(s): | Gröger, Victoria Emmer, Alexander  Staege, Martin Sebastian Cynis, Holger |
| Issue Date: | 2021 |
| Type: | Article |
| Language: | English |
| Abstract: | Human endogenous retroviruses (HERV) have been implicated in the pathogenesis of several nervous system disorders including multiple sclerosis and amyotrophic lateral sclerosis. The toxicity of HERV-derived RNAs and proteins for neuronal cells has been demonstrated. The involvement of HERV in the pathogenesis of currently incurable diseases might offer new treatment strategies based on the inhibition of HERV activities by small molecules or therapeutic antibodies. |
| URI: | https://opendata.uni-halle.de//handle/1981185920/122709 http://dx.doi.org/10.25673/120754 |
| Open Access: |  Open access publication |
| License: |  (CC BY 4.0) Creative Commons Attribution 4.0 |
| Journal Title: | Pharmaceuticals |
| Publisher: | MDPI |
| Publisher Place: | Basel |
| Volume: | 14 |
| Issue: | 1 |
| Original Publication: | 10.3390/ph14010070 |
| Appears in Collections: | Open Access Publikationen der MLU |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| pharmaceuticals-14-00070.pdf | 403.75 kB | Adobe PDF |  View/Open |