Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/38494
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DC Field | Value | Language |
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dc.contributor.author | Hage, Christoph | - |
dc.contributor.author | Iacobucci, Claudio | - |
dc.contributor.author | Götze, Michael | - |
dc.contributor.author | Sinz, Andrea | - |
dc.date.accessioned | 2021-09-27T09:05:27Z | - |
dc.date.available | 2021-09-27T09:05:27Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://opendata.uni-halle.de//handle/1981185920/38740 | - |
dc.identifier.uri | http://dx.doi.org/10.25673/38494 | - |
dc.description.abstract | Chemical cross-linking combined with mass spectrometry (XL-MS) and computational modeling has evolved as an alternative method to derive protein 3D structures and to map protein interaction networks. Special focus has been laid recently on the development and application of cross-linkers that are cleavable by collisional activation as they yield distinct signatures in tandem mass spectra. Building on our experiences with cross-linkers containing an MS-labile urea group, we now present the biuret-based, CID-MS/MS-cleavable cross-linker imidodicarbonyl diimidazole (IDDI) and demonstrate its applicability for protein cross-linking studies based on the four model peptides angiotensin II, MRFA, substance P, and thymopentin. | eng |
dc.description.sponsorship | Publikationsfond MLU | - |
dc.language.iso | eng | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.subject.ddc | 572 | - |
dc.title | A biuret‐derived, MS‐cleavable cross‐linking reagent for protein structural analysis : a proof‐of‐principle study | eng |
dc.type | Article | - |
local.versionType | publishedVersion | - |
local.bibliographicCitation.journaltitle | Journal of mass spectrometry | - |
local.bibliographicCitation.volume | 55 | - |
local.bibliographicCitation.issue | 1 | - |
local.bibliographicCitation.publishername | Wiley | - |
local.bibliographicCitation.publisherplace | Bognor Regis [u.a.] | - |
local.bibliographicCitation.doi | 10.1002/jms.4449 | - |
local.openaccess | true | - |
dc.identifier.ppn | 1690068523 | - |
local.bibliographicCitation.year | 2020 | - |
cbs.sru.importDate | 2021-09-27T09:03:37Z | - |
local.bibliographicCitation | Enthalten in Journal of mass spectrometry - Bognor Regis [u.a.] : Wiley, 1995 | - |
local.accessrights.dnb | free | - |
Appears in Collections: | Open Access Publikationen der MLU |
Files in This Item:
File | Description | Size | Format | |
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jms.4449.pdf | 4.37 MB | Adobe PDF | View/Open |