Please use this identifier to cite or link to this item:
http://dx.doi.org/10.25673/78146Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hoenke, Sophie | - |
| dc.contributor.author | Christoph, Martin A. | - |
| dc.contributor.author | Friedrich, Sander | - |
| dc.contributor.author | Heise, Niels | - |
| dc.contributor.author | Brandes, Benjamin | - |
| dc.contributor.author | Deigner, Hans-Peter | - |
| dc.contributor.author | Al-Harrasi, Ahmed | - |
| dc.contributor.author | Csuk, René | - |
| dc.date.accessioned | 2022-03-22T08:02:24Z | - |
| dc.date.available | 2022-03-22T08:02:24Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.uri | https://opendata.uni-halle.de//handle/1981185920/80100 | - |
| dc.identifier.uri | http://dx.doi.org/10.25673/78146 | - |
| dc.description.abstract | Pentacyclic triterpenoids oleanolic acid, ursolic acid, betulinic acid, and platanic acid were acetylated and converted into several amides 9–31; the cytotoxicity of which has been determined in sulforhodamine B assays employing seral human tumor cell lines and nonmalignant fibroblasts. Thereby, a betulinic acid/trans-1,4-cyclohexyldiamine amide showed excellent cytotoxicity (for example, EC50 = 0.6 μM for HT29 colon adenocarcinoma cells). | eng |
| dc.description.sponsorship | Publikationsfonds MLU | - |
| dc.language.iso | eng | - |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
| dc.subject.ddc | 547 | - |
| dc.title | The presence of a cyclohexyldiamine moiety confers cytotoxicity to pentacyclic triterpenoids | eng |
| dc.type | Article | - |
| local.versionType | publishedVersion | - |
| local.bibliographicCitation.journaltitle | Molecules | - |
| local.bibliographicCitation.volume | 26 | - |
| local.bibliographicCitation.issue | 7 | - |
| local.bibliographicCitation.publishername | MDPI | - |
| local.bibliographicCitation.publisherplace | Basel | - |
| local.bibliographicCitation.doi | 10.3390/molecules26072102 | - |
| local.openaccess | true | - |
| local.accessrights.dnb | free | - |
| Appears in Collections: | Open Access Publikationen der MLU | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| molecules-26-02102-v2.pdf | 1.54 MB | Adobe PDF |  View/Open |