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http://dx.doi.org/10.25673/103179
Titel: | Visceral to subcutaneous fat ratio predicts short-term mortality in patients with Covid 19 : a multicenter study |
Autor(en): | Surov, Alexey![]() Thormann, Maximilian ![]() Kardas, Hakan Hinnerichs, Mattes Omari, Jazan Cingöz, Eda Dursun, Memduh Kormaz, İnan Orhan, Çağrı Yildiz, Ömer ![]() Hocaoğlu, Elif Inci, Ercan Önder, Hakan Erk, Hamdullah Chousein, Ougkour Sasani, Hadi Gönen, Korcan Aysun Pech, Maciej ![]() Wienke, Andreas ![]() |
Erscheinungsdatum: | 2023 |
Art: | Artikel |
Sprache: | Englisch |
Zusammenfassung: | Objective: To evaluate the association of body composition parameters with outcomes in Covid-19. Methods: 173 patients hospitalized for Covid-19 infection in 6 European centers were included in this retrospective study. Measurements were performed at L3-level and comprised skeletal muscle index (SMI), muscle density (MD), and adipose tissue measurements [visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intramuscular adipose tissue (IMAT), visceral-to-subcutaneous-adipose-tissue-area-ratio (VSR)]. The association with mortality, the need for intubation (MV), and the need for admission to ICU within 30 days were evaluated. Results: Higher SAT density was associated with a greater risk of MV (OR = 1.071, 95%CI=(1.034;1.110), p < 0.001). Higher VAT density was associated with admission to ICU (OR = 1.068, 95%CI=(1.029;1.109), p < 0.001). Higher MD was a protective factor for MV and ICU admission (OR = 0.914, 95%CI=(0.870;0.960), p < 0.001; OR = 0.882, 95%CI=(0.832;0.934), p = 0.028). Higher VSR was associated with mortality (OR = 2.147, 95%CI=(1.022;4.512), p = 0.044). Male sex showed the strongest influence on the risk of ICU admission and MV. SMI was not associated with either parameter. Conclusion: In patients hospitalized for Covid-19 infection, higher VSR seems to be a strong prognostic factor of short-term mortality. Weak associations with clinical course were found for MD and adipose tissue measurements. Male sex was the strongest prognostic factor of adverse clinical course. |
URI: | https://opendata.uni-halle.de//handle/1981185920/105131 http://dx.doi.org/10.25673/103179 |
Open-Access: | ![]() |
Nutzungslizenz: | ![]() |
Journal Titel: | BJR |
Verlag: | Wiley |
Verlagsort: | Bognor Regis |
Band: | 96 |
Heft: | 1144 |
Originalveröffentlichung: | 10.1259/bjr.20220869 |
Enthalten in den Sammlungen: | Open Access Publikationen der MLU |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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bjr.20220869.pdf | 334.95 kB | Adobe PDF | ![]() Öffnen/Anzeigen |