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http://dx.doi.org/10.25673/103296
Titel: | On frailty and accelerated aging during SARS-Cov-2 : senescence |
Autor(en): | Müller-Werdan, Ursula![]() Polidori, M. Cristina Simm, Andreas ![]() |
Erscheinungsdatum: | 2023 |
Art: | Artikel |
Sprache: | Englisch |
Zusammenfassung: | The COVID-19 pandemic is a burden for the worldwide healthcare systems. Whereas a clear age-dependent mortality can be observed, especially multimorbid and frail persons are at an increased risk. As bio-functional rather than calendrical age is in the meanwhile known to play a crucial role for COVID-19-related outcomes, aging-associated risk factors, overall prognosis and physiological age-related changes should be systematically considered for clinical decision-making. In this overview, we focus on cellular senescence as a major factor of biological aging, associated with organ dysfunction and increased inflammation (inflammaging). |
URI: | https://opendata.uni-halle.de//handle/1981185920/105248 http://dx.doi.org/10.25673/103296 |
Open-Access: | ![]() |
Nutzungslizenz: | ![]() |
Journal Titel: | Aging clinical and experimental research |
Verlag: | Heidelberg : Springer |
Verlagsort: | Berlin |
Band: | 35 |
Originalveröffentlichung: | 10.1007/s40520-023-02364-4 |
Seitenanfang: | 907 |
Seitenende: | 912 |
Enthalten in den Sammlungen: | Open Access Publikationen der MLU |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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s40520-023-02364-4.pdf | 594.34 kB | Adobe PDF | ![]() Öffnen/Anzeigen |