Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/110744
Title: Free amino acid contents of selected Ethiopian plant and fungi species : a search for alternative natural free amino acid sources for cosmeceutical applications
Author(s): Kahsay, Birhanu Nigusse
Ziegler, Jörg
Imming, PeterLook up in the Integrated Authority File of the German National Library
Gebre-Mariam, Tsige
Neubert, Reinhard H. H.Look up in the Integrated Authority File of the German National Library
Moeller, Lucie
Issue Date: 2021
Type: Article
Language: English
Abstract: Free amino acids (FAAs), the major constituents of the natural moisturizing factor (NMF), are very important for maintaining the moisture balance of human skin and their deficiency results in dry skin conditions. There is a great interest in the identification and use of nature-based sources of these molecules for such cosmeceutical applications. The objective of the present study was, therefore, to investigate the FAA contents of selected Ethiopian plant and fungi species; and select the best sources so as to use them for the stated purpose. About 59 different plant species and oyster mushroom were included in the study and the concentrations of 27 FAAs were analyzed. Each sample was collected, lyophilized, extracted using aqueous solvent, derivatized with Fluorenylmethoxycarbonyl chloride (Fmoc-Cl) prior to solid-phase extraction and quantified using Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometric (LC-ESI–MS/MS) system. All the 27 FAAs were detected in most of the samples. The dominant FAAs that are part of the NMF were found at sufficiently high concentration in the mushroom and some of the plants. This indicates that FAAs that could be included in the preparations for the management of dry skin condition can be obtained from a single natural resource and the use of these resources for the specified purpose have both economic and therapeutic advantage in addition to fulfilling customer needs.
URI: https://opendata.uni-halle.de//handle/1981185920/112699
http://dx.doi.org/10.25673/110744
Open Access: Open access publication
License: (CC BY 4.0) Creative Commons Attribution 4.0(CC BY 4.0) Creative Commons Attribution 4.0
Journal Title: Amino acids
Publisher: Springer
Publisher Place: Wien [u.a.]
Volume: 53
Issue: 7
Original Publication: 10.1007/s00726-021-03008-5
Page Start: 1105
Page End: 1122
Appears in Collections:Open Access Publikationen der MLU

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