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Titel: Significant improvement in neuropsychological functions after awake craniotomy in a patient with Oligodendroglioma : a case report
Autor(en): Thomas, MareikeIn der Gemeinsamen Normdatei der DNB nachschlagen
Scheer, Maximilian
Spindler, Kai
Nieberlein, Laura
Hartwigsen, GesaIn der Gemeinsamen Normdatei der DNB nachschlagen
Gussew, Alexander
Schob, StefanIn der Gemeinsamen Normdatei der DNB nachschlagen
Prell, Julian
Strauss, ChristianIn der Gemeinsamen Normdatei der DNB nachschlagen
Rampp, StefanIn der Gemeinsamen Normdatei der DNB nachschlagen
Erscheinungsdatum: 2023
Art: Artikel
Sprache: Englisch
Zusammenfassung: Objective: The goal of awake craniotomy in glioma patients is sparing of cognitive function. Previous investigations suggest that patients in the postoperative state may reach their preoperative level regarding domain-based criteria. Data on significant postoperative improvement beyond the preoperative level is sparse. This article examines the prospective neuropsychological assessment of a glioma patient who underwent awake craniotomy and has shown functional improvement exceeding preoperative levels. Methods: A 34-year-old patient with high premorbid cognitive function level who underwent awake craniotomy for left frontal oligodendroglioma was neuropsychologically assessed and took part in a fMRI-examination at 3 different time points. Results: Preoperative examination revealed severe isolated impairment of working memory, long-term narrative memory in free recall and recognition, and alertness with intact language production and comprehension. After transient global aphasia in the postoperative state, the follow-up examination showed significant improvement in memory and attention exceeding the preoperative level. Conclusions: Tumor location is an important factor in terms of surgical procedures. Cognitive impairment is, however, not always associated with a specific location. Mechanical pressure of the tumor might have led to the isolated consolidation deficit which fully recovered after tumor removal. Psychological disorders should be taken into account regarding prodromal symptoms of neurooncological diseases.
URI: https://opendata.uni-halle.de//handle/1981185920/113777
http://dx.doi.org/10.25673/111820
Open-Access: Open-Access-Publikation
Nutzungslizenz: (CC BY 4.0) Creative Commons Namensnennung 4.0 International(CC BY 4.0) Creative Commons Namensnennung 4.0 International
Journal Titel: Interdisciplinary Neurosurgery
Verlag: Elsevier
Verlagsort: Amsterdam [u.a.]
Band: 33
Originalveröffentlichung: 10.1016/j.inat.2023.101796
Enthalten in den Sammlungen:Open Access Publikationen der MLU

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