Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/63027
Title: Cardiovascular risk factors, living and ageing in Halle : the CARLA study
Author(s): Hassan, Lamiaa
Efremov, Ljupcho
Großkopf, Anne
Kartschmit, NadjaLook up in the Integrated Authority File of the German National Library
Medenwald, DanielLook up in the Integrated Authority File of the German National Library
Schott, ArtjomLook up in the Integrated Authority File of the German National Library
Schmidt-Pokrzywniak, AndreaLook up in the Integrated Authority File of the German National Library
Lacruz, Maria E.
Tiller, DanielLook up in the Integrated Authority File of the German National Library
Kraus, Frank BernhardLook up in the Integrated Authority File of the German National Library
Greiser, Karin HalinaLook up in the Integrated Authority File of the German National Library
Härting, Johannes
Werdan, KarlLook up in the Integrated Authority File of the German National Library
Sedding, DanielLook up in the Integrated Authority File of the German National Library
Simm, AndreasLook up in the Integrated Authority File of the German National Library
Nuding, SebastianLook up in the Integrated Authority File of the German National Library
Kluttig, AlexanderLook up in the Integrated Authority File of the German National Library
Mikolajczyk, RafaelLook up in the Integrated Authority File of the German National Library
Issue Date: 2022
Type: Article
Language: English
Abstract: The CARLA study (Cardiovascular Disease, Living and Ageing in Halle) is a longitudinal population-based cohort study of the general population of the city of Halle (Saale), Germany. The primary aim of the cohort was to investigate risk factors for cardiovascular diseases based on comprehensive cardiological phenotyping of study participants and was extended to study factors associated with healthy ageing. In total, 1779 probands (812 women and 967 men, aged 45–83 years) were examined at baseline (2002–2005), with a first and second follow-up performed 4 and 8 years later. The response proportion at baseline was 64.1% and the reparticipation proportion for the first and second follow-up was 86% and 77% respectively. Sixty-four percent of the study participants were in retirement while 25% were full- or partially-employed and 11% were unemployed at the time of the baseline examination. The currently running third follow-up focuses on the assessment of physical and mental health, with an intensive 4 h examination program, including measurement of cardiovascular, neurocognitive, balance and gait parameters. The data collected in the CARLA Study resulted in answering various research questions in over 80 publications, of which two thirds were pooled analyses with other similar population-based studies. Due to the extensiveness of information on risk factors, subclinical conditions and evident diseases, the biobanking concept for the biosamples, the cohort representativeness of an elderly population, and the high level of quality assurance, the CARLA cohort offers a unique platform for further research on important indicators for healthy ageing.
URI: https://opendata.uni-halle.de//handle/1981185920/64978
http://dx.doi.org/10.25673/63027
Open Access: Open access publication
License: (CC BY 4.0) Creative Commons Attribution 4.0(CC BY 4.0) Creative Commons Attribution 4.0
Sponsor/Funder: Publikationsfonds MLU
Journal Title: European journal of epidemiology
Publisher: Springer Nature Switzerland AG
Publisher Place: [Cham]
Volume: 37
Issue: 1
Original Publication: 10.1007/s10654-021-00824-7
Page Start: 103
Page End: 116
Appears in Collections:Open Access Publikationen der MLU

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