Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/117858
Title: Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations
Author(s): Muir, Tobian
Wohlgemuth, Walter A.Look up in the Integrated Authority File of the German National Library
Cemažar, MajaLook up in the Integrated Authority File of the German National Library
Bertino, Giulia
Groselj, Ales
Ratnam, Lakshmi A.
McCafferty, Ian
Wildgruber, MoritzLook up in the Integrated Authority File of the German National Library
Gebauer, BernhardLook up in the Integrated Authority File of the German National Library
Terlizzi, Francesca
Zanasi, Alessandro
Sersa, Gregor
Issue Date: 2024
Type: Article
Language: English
Abstract: Background: Bleomycin ElectroScleroTherapy (BEST) is a new approach in the treatment of vascular malformations. After bleomycin is administered to the malformation, electric pulses are applied to the target area to enhance the effectiveness of bleomycin. The mode of action is comparable to the effect of electrochemotherapy on tumour vasculature. For the wider and safer use of BEST in the clinical treatment of low-flow vascular malformations, this Current Operating Procedure (COP) is being prepared. It is a proposal for the clinical standardisation of BEST using the Cliniporator® as the electrical pulse generator with its associated electrodes. The electrical parameters considered in this protocol are those validated by the European Standard Operating Procedures for Electrochemotherapy (ESOPE) with the Cliniporator®. Conclusions: General requirements are proposed, and, depending on the type of lesion, local skills and the availability of radiological equipment, two technical approaches of BEST are described based on ultrasound guided intervention or combined ultrasound and fluoroscopic guided intervention.
URI: https://opendata.uni-halle.de//handle/1981185920/119818
http://dx.doi.org/10.25673/117858
Open Access: Open access publication
License: (CC BY 4.0) Creative Commons Attribution 4.0(CC BY 4.0) Creative Commons Attribution 4.0
Journal Title: Radiology and oncology
Publisher: Sciendo
Publisher Place: Warsaw
Volume: 58
Issue: 4
Original Publication: 10.2478/raon-2024-0061
Page Start: 469
Page End: 479
Appears in Collections:Open Access Publikationen der MLU