Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/86334
Title: H3K9 demethylation is required for reproduction in Arabidopsis
Author(s): Cheng, JinpingLook up in the Integrated Authority File of the German National Library
Referee(s): Jiang, Hua
Shen, Wenhui
Granting Institution: Martin-Luther-Universität Halle-Wittenberg
Issue Date: 2022
Extent: 1 Online-Ressource (111Seiten)
Type: HochschulschriftLook up in the Integrated Authority File of the German National Library
Type: Doctoral thesis
Exam Date: 2022-05-16
Language: English
URN: urn:nbn:de:gbv:3:4-1981185920-882873
Abstract: Meiose ist ein entscheidender Prozess für die Reproduktion in Eukaryoten. Die Arabidopsis-Meiose ist tolerant gegenüber dem Verlust von H3K9me2. Es ist jedoch unklar, ob die Entfernung von H3K9me2 für die Meiose erforderlich ist. In dieser Studie fand ich heraus, dass die Histon-Demethylasen IBM1 und JMJ27 erforderlich sind, um H3K9me2 aus meiotischen Genen, einschließlich ZIP4 und SHOC1, zu entfernen. PDS5-Proteine, die Kohäsin-Cofaktoren, wirken stromabwärts IBM1 und JMJ27, um die meiotische Genexpression zu aktivieren. Außerdem fand ich heraus, dass IBM1 und JMJ27 für die Pollenwandbildung erforderlich sind.
Meiosis is a crucial process for reproduction in eukaryotes. Arabidopsis meiosis is tolerant to loss of H3K9me2. However, it is unclear whether removing H3K9me2 is required for meiosis. In this study, I found that histone demethylases IBM1 and JMJ27 are required to remove H3K9me2 from meiotic genes, including ZIP4 and SHOC1. PDS5 proteins, the cohesin cofactors, act downstream of IBM1 and JMJ27 to activate meiotic gene expression. Besides, I also found that IBM1 and JMJ27 are required for pollen wall formation.
URI: https://opendata.uni-halle.de//handle/1981185920/88287
http://dx.doi.org/10.25673/86334
Open Access: Open access publication
License: In CopyrightIn Copyright
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